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Peer-reviewed veterinary case report

Carcinoma in situ and seminoma in equine testis.

Journal:
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
Year:
1998
Authors:
Veeramachaneni, D N & Sawyer, H R
Affiliation:
Colorado State University · United States
Species:
horse

Plain-English summary

This study discusses a case involving a stallion that had a condition called cryptorchidism, where one of the testicles is not in its normal position. Researchers found unusual cells in the testicle that looked similar to a type of early-stage testicular cancer seen in humans, known as carcinoma in situ. These atypical cells were linked to a developing seminoma, which is a type of testicular tumor. This is the first time such findings have been reported in horses. The study highlights the importance of recognizing these changes in equine testicular health.

Abstract

The presence of atypical germ cells resembling carcinoma in situ of human testis is reported for the first time in an unilaterally cryptorchid stallion. These cells were found in association with developing intratubular seminoma indicating they represented carcinoma in situ.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/9524577/