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Peer-reviewed veterinary case report

Canine Uterine Leiomyoma with Epithelial Tissue Foci, Adenomyosis, and Cystic Endometrial Hyperplasia

Journal:
Case Reports in Veterinary Medicine
Year:
2011
Authors:
George S. Karagiannis et al.
Affiliation:
School of Veterinary Medicine, Aristotle University of Thessalonki, Aristotle University of Thessalonki, 54124 Thessaloníki, Greece · GB
Species:
dog

Plain-English summary

An 11-year-old female Labrador Retriever was brought in because she had been experiencing occasional vaginal bleeding for about six months. During surgery to explore her abdomen, the veterinarian found two distinct masses in her uterus. One mass was a typical type of tumor called a leiomyoma, while the other had some unusual features, including areas of epithelial tissue, mild adenomyosis (a condition where the inner lining of the uterus grows into the muscle), and cystic endometrial hyperplasia (a thickening of the uterine lining). This combination of findings had not been seen before in dogs, but it resembled certain cases of similar conditions in humans. The treatment and outcome details were not provided, but the findings suggest a complex situation that may require careful monitoring.

Abstract

An 11-year-old Labrador Retriever bitch with a history of intermittent, sanguineous vaginal discharge of a six-month duration was presented. During exploratory laparotomy, two well-delineated, intramural masses were identified bilaterally in the uterine horns. Histopathologic examination of the mass on the left horn showed that it was a typical leiomyoma. However, the second mass appeared with an unusual coexistence of histological lesions, involving epithelial tissue foci, mild focal adenomyosis, and cystic endometrial hyperplasia. Interestingly, such combination was never encountered before in dogs. Although uterine leiomyoma is quite usual in the reproductive system of female dogs, this case resembled relevant cases of human uterine adenomyomas in morphology, and thus it was offered a similar tentative diagnosis.

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Original publication: https://doi.org/10.1155/2011/901874