Peer-reviewed veterinary case report
Blindness associated with nasal/paranasal lymphoma in a stallion.
- Journal:
- The Journal of veterinary medical science
- Year:
- 2017
- Authors:
- Sano, Yuto et al.
- Affiliation:
- Department of Veterinary Pathology · Japan
- Species:
- horse
Plain-English summary
A 29-year-old stallion was found to be blind in both eyes after having a long-term problem with thick, pus-like drainage from his nose. A tumor was discovered in his right nasal cavity and sinuses, which had grown large enough to invade and damage the right optic nerve and press on the left optic nerve. Tests showed that the optic nerves were deteriorating, and the tumor was identified as a type of cancer called diffuse large B-cell lymphoma. This case is notable because it is the first documented instance of a horse going blind due to this type of cancer affecting the nasal area. The treatment details and outcome were not provided in the abstract.
Abstract
A 29-year-old stallion presented with bilateral blindness following the chronic purulent nasal drainage. The mass occupied the right caudal nasal cavity and right paranasal sinuses including maxillary, palatine and sphenoidal sinuses, and the right-side turbinal and paranasal septal bones, and cribriform plate of ethmoid bone were destructively replaced by the mass growth. The right optic nerve was invaded and involved by the mass, and the left optic nerve and optic chiasm were compressed by the mass which was extended and invaded the skull base. Histologically, the optic nerves and optic chiasm were degenerated, and the mass was diagnosed as lymphoma which was morphologically and immunohistochemically classified as a diffuse large B-cell lymphoma. Based on these findings, the cause of the blindness in the stallion was concluded to be due to the degeneration of the optic nerves and chiasm associated with lymphoma occurring in the nasal and paranasal cavities. To the best of our knowledge, this is the first report of the equine blindness with optic nerve degeneration accompanied by lymphoma.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/28163275/