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Peer-reviewed veterinary case report

<b>Platelet-rich plasma application for the management of early-stage Canine Legg-calvé-perthes disease: A clinical case report</b>

Journal:
Open Veterinary Journal
Year:
2025
Authors:
Sinkevičius, Viktoras et al.
Species:
dog

Abstract

Background: Legg-Calvé-Perthes Disease (LCPD) is characterized by ischemic necrosis of the femoral head, primarily affecting small breed dogs. Case Description: An 11-month-old, female Toy Poodle presented with hindlimb lameness due to LCPD, previously treated unsuccessfully with NSAIDs. Platelet-Rich Plasma (PRP) was administered intra-articularly. Clinical evaluations included lameness scoring, range of motion (ROM), thigh girth measurements, and radiographic assessment. Conclusion: PRP administration resulted in significant clinical improvement, reduction in lameness, pain relief, cessation of bone lysis, and increased muscle mass by day 44 post-treatment.

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Original publication: https://doi.org/10.5455/ovj.2025.v15.i10.60