Peer-reviewed veterinary case report
Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele.
- Journal:
- Tissue antigens
- Year:
- 2006
- Authors:
- Kennedy, L J et al.
- Affiliation:
- University of Manchester · United Kingdom
- Species:
- dog
Abstract
Dogs exhibit a range of immune-mediated conditions including a lymphocytic thyroiditis which has many similarities to Hashimoto's thyroiditis in man. We have recently reported an association in Doberman Pinschers between canine hypothyroidism and a rare DLA class II haplotype that contains the DLA-DQA1*00101 allele. We now report a further series of 173 hypothyroid dogs in a range of breeds where a significant association with DLA-DQA1*00101 is shown.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16774545/