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Peer-reviewed veterinary case report

Arrhythmogenic Right Ventricular Cardiomyopathy in the Boxer Dog: An Update.

Journal:
The Veterinary clinics of North America. Small animal practice
Year:
2017
Authors:
Meurs, Kathryn M
Affiliation:
Department of Clinical Sciences · United States
Species:
dog

Abstract

Arrhythmogenic right ventricular cardiomyopathy is an inheritable form of myocardial disease characterized most commonly by ventricular tachycardias, syncope, and sometimes systolic dysfunction and heart failure. A genetic mutation in the striatin gene has been identified in many affected dogs. Dogs with only one copy of the mutation (heterozygous) have a variable prognosis, with many dogs remaining asymptomatic or being successfully managed on antiarrhythmic drugs for years. Dogs that are homozygous for the mutation seem to have a worse prognosis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/28647112/