Peer-reviewed veterinary case report
Appraisal of the porcine kidney autotransplantation model.
- Journal:
- Frontiers in bioscience (Elite edition)
- Year:
- 2012
- Authors:
- Post, Ivo C J H et al.
- Affiliation:
- Department of Surgery (Surgical Laboratory) · Netherlands
Abstract
Animal models are extensively used for transplantation related research, especially kidney transplantation. Porcine autotransplantation models are considered to be favorable regarding translatability to the human setting. The key determinants for translatability of the model are discussed, comprising animal age, development, anatomy, anesthesia and surgical protocols, and perioperative care. With the detailed discussion of these determinants and the pitfalls in diagnosing animal discomfort, an attempt is made to provide a uniform porcine kidney autotransplantation model with tools to improve currently used models.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22201959/