Peer-reviewed veterinary case report
Antiparasitic treatment with itraconazole and amiodarone in 2 dogs with severe, symptomatic Chagas cardiomyopathy.
- Journal:
- Journal of veterinary internal medicine
- Year:
- 2022
- Authors:
- Malcolm, Elizabeth L et al.
- Affiliation:
- Department of Small Animal Clinical Sciences · United States
- Species:
- dog
Abstract
Chagas cardiomyopathy, caused by the protozoal parasite Trypanosoma cruzi, is characterized by arrhythmias, myocardial damage, heart failure, and sudden death. We describe 2 dogs with severe, symptomatic Chagas cardiomyopathy characterized by myocardial dysfunction and electrocardiographic abnormalities that were managed with a combination of cardiac medications and antiparasitic treatment with itraconazole and amiodarone. Both dogs died suddenly within 6 months of diagnosis. These cases highlight the need for early detection of Chagas disease in dogs and continued research to develop effective antiparasitic treatment protocols.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/35388923/