Peer-reviewed veterinary case report
Antibiotic susceptibility of bacterial isolates from 502 dogs with respiratory signs.
- Journal:
- The Veterinary record
- Year:
- 2015
- Authors:
- Rheinwald, M et al.
- Affiliation:
- Clinic of Small Animal Medicine · Germany
- Species:
- dog
Plain-English summary
This study looked at samples from 502 dogs showing signs of respiratory issues to find out what types of bacteria were present and how sensitive they were to antibiotics. They found that in about 35 percent of the samples, no bacteria were detected. The most common bacteria identified included Streptococcus, Enterobacteriaceae (which includes E. coli), Staphylococcus, Pasteurella, and Pseudomonas, with Bordetella bronchiseptica being a key respiratory pathogen in 8 percent of cases. The researchers found that the antibiotic enrofloxacin was effective against 86 percent of the bacteria, while amoxicillin combined with clavulanic acid worked well for 92 percent of the Gram-positive bacteria. Based on these findings, these antibiotics are recommended as first-line treatments for dogs with bacterial infections in their lower respiratory tract.
Abstract
The aim of this study was to investigate the prevalence of bacterial species isolated from bronchoalveolar lavage fluid (BALF) samples taken from dogs with respiratory signs and to determine their antibiotic susceptibility. Clinical cases were included in the study if they showed signs of respiratory disease and data relating to bacterial culture and susceptibility of BALF samples were available. The medical records of 493 privately owned dogs that were presented between January 1989 and December 2011 were evaluated retrospectively. In 35 per cent of samples, no bacteria were cultured. Bacteria isolated from culture-positive samples included Streptococcus species (31 per cent of positive cultures), Enterobacteriaceae (30 per cent, including Escherichia coli (15 per cent)), Staphylococcus species (19 per cent), Pasteurella species (16 per cent) and Pseudomonas species (14 per cent). Bordetella bronchiseptica as a primary respiratory pathogen was isolated in 8 per cent of cases. Enrofloxacin showed the best susceptibility pattern; 86 per cent of all isolates and 87 per cent of Gram-negative bacteria were susceptible to this antibiotic. Amoxicillin/clavulanic acid yielded the best susceptibility pattern in Gram-positive bacteria (92 per cent). Therefore, these antibiotics can be recommended for empirical or first-line treatment in dogs with bacterial lower respiratory tract infections.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/25467146/