Peer-reviewed veterinary case report
Antibacterial properties of magnesium in vitro and in an in vivo model of implant-associated methicillin-resistant Staphylococcus aureus infection.
- Journal:
- Antimicrobial agents and chemotherapy
- Year:
- 2014
- Authors:
- Li, Yang et al.
- Affiliation:
- Department of Orthopaedic Surgery · China
- Species:
- rodent
Abstract
Periprosthetic infection remains a challenging clinical complication. We investigated the antibacterial properties of pure (99.9%) magnesium (Mg) in vitro and in an in vivo rat model of implant-related infection. Mg was highly effective against methicillin-resistant Staphylococcus aureus-induced osteomyelitis and improved new peri-implant bone formation. Bacterial icaA and agr RNAIII transcription levels were also assessed to characterize the mechanism underlying the antibacterial properties of the Mg implant.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/25288077/