Peer-reviewed veterinary case report
Antiarthritic effects of Ajuga bracteosa Wall ex Benth. in acute and chronic models of arthritis in albino rats.
- Journal:
- Asian Pacific journal of tropical biomedicine
- Year:
- 2012
- Authors:
- Kaithwas, Gaurav et al.
- Affiliation:
- Department of Pharmaceutical Sciences · India
- Species:
- rodent
Abstract
OBJECTIVE: To evaluate the antiarthritic activity of Ajuga bracteosa using albino rats. METHODS: The antiarthritic activity of 70% ethanolic extract of Ajuga bracteosa (EEAB) was evaluated against turpentine oil- and formaldehyde- induced acute non immunological and complete freund's adjuvant (CFA)-induced chronic immunological arthritis in albino rats. RESULTS: EEAB showed a significant (P<0.05) and dose dependent inhibitory effect against acute and chronic models of arthritis. EEAB exhibited better antiarthritic activity than the standard aspirin. CONCLUSIONS: EEAB exhibits a significant and promising antiarthritic activity against acute and chronic arthritis and supports the traditional use of Ajuga bracteosa for rheumatism and other inflammatory diseases.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/23569895/