Peer-reviewed veterinary case report
Analytical performance of commercially-available assays for feline insulin-like growth factor 1 (IGF-1), adiponectin and ghrelin measurements.
- Journal:
- Journal of feline medicine and surgery
- Year:
- 2012
- Authors:
- Tvarijonaviciute, Asta et al.
- Affiliation:
- Department of Animal Medicine and Surgery · Spain
- Species:
- cat
Abstract
The objective of this study was to evaluate three commercially-available human assays for the determination of adiponectin, ghrelin and insulin-like growth factor 1 (IGF-1) concentrations in feline serum samples. Intra- and interassay coefficients of variation were lower than 20%, 15% and 6% for adiponectin, ghrelin and IGF-1 assays, respectively. Dilutions of feline serum pools resulted in linear regression equations in all kits. Mean recovery of adiponectin, ghrelin and IGF-1 assays were 107%, 102% and 105%, respectively. Significant differences were detected in adiponectin and ghrelin concentrations between lean and obese cats (P <0.05 in both cases), but there was no difference in IGF-1 concentrations (P = 0.12).
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22314090/