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Peer-reviewed veterinary case report

Anal sac mast cell tumor in a dog.

Journal:
The Canadian veterinary journal = La revue veterinaire canadienne
Year:
2023
Authors:
Perchick, Jonathan P & Beswick, Joseph A
Affiliation:
Rose City Veterinary Hospital · United States
Species:
dog

Plain-English summary

An 11-year-old male mixed-breed dog was found to have a mass in one of his anal sacs. The vet successfully removed the mass through surgery, and tests showed it was a type of cancer called a mast cell tumor. After the surgery, the dog recovered well, and follow-up checks at 4, 8, and 12 months showed no signs of cancer returning. This case is notable because mast cell tumors in the anal sac are not commonly reported in dogs. Overall, the treatment was effective, and the dog remained healthy after the surgery.

Abstract

An 11-year-old castrated mixed-breed dog was diagnosed with a unilateral anal sac mass. Anal sacculectomy was performed without complication. Histopathology of the mass was consistent with a well-differentiated mast cell tumor. Analyses for the Ki-67 protein, KIT expression pattern, and the presence ofmutations were done. Recovery from surgery was unremarkable and repeat staging revealed no evidence of mast cell disease at 4, 8, and 12 mo after surgery. To the authors' knowledge, primary mast cell neoplasia of the anal sac has not previously been reported in the veterinary literature. Key clinical message: Although mast cell tumors of the perineal region are commonly encountered in veterinary practice, the anal sac represents a novel location for this disease. Cytology of anal sac masses can be a useful diagnostic tool to confirm the diagnosis, guide staging, and assist in treatment decisions.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/37663027/