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Peer-reviewed veterinary case report

Amniotic membrane transplantation for the reconstruction of the ocular surface in three cases.

Journal:
Veterinary ophthalmology
Year:
2005
Authors:
Barros, Paulo S M et al.
Affiliation:
School of Veterinary Medicine · Brazil
Species:
dog

Plain-English summary

This study looked at using amniotic membrane, which is a tissue from the inner layer of the placenta, to help repair eye problems in two dogs and a cat. The first case involved an 11-year-old female Yorkshire terrier with a serious eye condition that caused damage to the cornea. After surgery, which included applying the amniotic membrane, the eye showed only mild scarring after 80 days. The second case was a 4-year-old female Siamese cat that had issues with both eyes due to a previous illness; after surgery and the amniotic membrane transplant, there was some scarring noted after a month. The last case was a 6-year-old female terrier with a mass on her eye that was removed and treated with the amniotic membrane, leading to a good healing outcome with minimal issues. Overall, the use of amniotic membrane for eye repairs in these pets showed promising results with good healing and little scarring.

Abstract

This paper describes the use of amniotic membrane in the reconstructive surgical repair of generalized keratomalacia, ankyloblepharon, and after fibrous histiocytoma removal in two dogs and a cat. Case 1 was an 11-year-old female Yorkshire terrier with severe bullous keratomalacia in the left eye (OS). A frozen canine amniotic membrane graft and a third eyelid flap were applied. At day 80 postoperatively, only a mild scar and corneal vascularization were present. Case 2 was a 4-year-old female Siamese cat with symblepharon of both eyes after rhinotracheitis. Resection of the conjunctiva and frozen canine amniotic membrane transplant were performed. One month later, there was a little corneal scarring and corneal vascularization. Case 3 was a 6-year-old female terrier with a scleral and corneal mass at the 11-12 o'clock position (OS). Resection of the mass and amniotic membrane transplantation were performed. The mass was a fibrous histiocytoma localized to the sclera and cornea. This eye healed with mild conjunctivalization and no pigmentation. Amniotic membrane transplantation can be used as a method of reconstruction of the ocular surface with good repair of the cornea and minimal scarring in small animals.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/15910372/