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Peer-reviewed veterinary case report

Acute myelogenous leukaemia in a mare.

Journal:
Australian veterinary journal
Year:
1997
Authors:
Ringger, N C et al.
Affiliation:
Department of Large Animal Clinical Sciences · United States
Species:
horse

Plain-English summary

A 5-year-old Thoroughbred mare had been losing weight for four weeks and had a fever. During a check-up, the veterinarian found a large active foal, a thickened spleen, and an abdominal mass. Blood tests showed low white blood cell counts, mild anemia, very low platelet counts, and high levels of a protein that indicates inflammation. Tests on her bone marrow confirmed she had acute myelogenous leukemia, a type of cancer. Unfortunately, her condition worsened despite treatment, and she was humanely put to sleep.

Abstract

A 5-year-old Thoroughbred mare presented with a 4 week history of weight loss, fever and leukopenia. Rectally, a large active foetus, thickened spleen and an abdominal mass were palpated. Leukopenia, mild anaemia, marked thrombocytopenia and hyperfibrinogenaemia were found. Cytology and cytochemical staining of a bone marrow aspirate supported a diagnosis of acute myelogenous leukaemia. The mare deteriorated despite medical therapy and was humanely euthanased.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/9196816/