Peer-reviewed veterinary case report
Activation of Guinea Pig Herpesvirus Antigen in Leukemic Lymphoblasts of Guinea Pig
- Journal:
- Journal of Virology
- Year:
- 1972
- Authors:
- Nayak, D. P.
- Affiliation:
- Department of Medical Microbiology and Immunology, University of California at Los Angeles School of Medicine, Los Angeles, California 90024 · United States
- Species:
- rodent
Abstract
Herpesvirus (GPHV) antigen is either present in very small amounts, or absent in leukemic lymphoblasts taken directly from strain 2 guinea pigs. However, after maintenance in tissue culture for 72 hr, almost 100% of these lymphoblasts contained GPHV antigen. The expression of GPHV antigen could be demonstrated by indirect immunofluorescent technique as well as by the direct 125 I labeled antibody technique. However, infectious virus or virus capsids could not be detected in these cells either by infectivity tests or electron microscopy.
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Search related cases →Original publication: https://doi.org/10.1128/jvi.10.5.933-936.1972