Peer-reviewed veterinary case report
Acquired idiopathic laryngeal paralysis as a prominent feature of generalised neuromuscular disease in 39 dogs.
- Journal:
- The Veterinary record
- Year:
- 2006
- Authors:
- Jeffery, N D et al.
- Affiliation:
- Department of Veterinary Medicine · United Kingdom
- Species:
- dog
Plain-English summary
In a study involving 39 dogs with a condition called acquired idiopathic laryngeal paralysis, which affects their ability to breathe properly, researchers looked at how well they responded to treatment. They found that while some dogs had surgery to help with their breathing, many still showed signs of weakness and had trouble exercising afterward. Further tests on 22 of these dogs revealed that they all had some neurological issues, but there was little indication that specific problems meant they wouldn't recover fully. None of the dogs tested positive for a certain antibody linked to a serious muscle condition, and only a few had thyroid problems. Overall, the outcomes varied, and many dogs did not fully regain their exercise ability after treatment.
Abstract
A retrospective evaluation of 17 dogs treated surgically for idiopathic acquired laryngeal paralysis demonstrated a marked variability in outcome, with many dogs continuing to exhibit weakness and exercise tolerance. In a subsequent prospective study, 22 consecutive affected dogs were tested for neurological deficits by neurological examination, electrodiagnostic evaluation, and blood analysis to measure thyroxine and thyroid-stimulating hormone and to detect any evidence of myasthenia gravis. Clinical neurological deficits and/or electrodiagnostic abnormalities were found in each case. There was limited evidence that specific neurological deficits were associated with a poor prognosis for full recovery of exercise tolerance. None of the dogs was positive for anti-acetylcholine receptor antibodies, and only three showed evidence of thyroid dysfunction.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16400098/