Peer-reviewed veterinary case report
A vaccine prepared from a non-pathogenic H5N1 influenza virus strain from the influenza virus library conferred protective immunity to chickens against the challenge with antigenically drifted highly pathogenic avian influenza virus.
- Journal:
- The Japanese journal of veterinary research
- Year:
- 2011
- Authors:
- Samad, Rozanah Asmah Abdul et al.
- Affiliation:
- Department of Disease Control · Japan
- Species:
- bird
Abstract
Inactivated influenza virus vaccine prepared from a non-pathogenic influenza virus strain A/duck/Hokkaido/Vac-1/2004 (H5N1) from the virus library conferred protective immunity to chickens against the challenge of antigenically drifted highly pathogenic avian influenza virus (HPAIV), A/whooper swan/Hokkaido/1/2008 (H5N1). The efficacy of the vaccine was comparable to that prepared from genetically modified HPAIV strain deltaRRRRK rg-A/ whooper swan/Mongolia/3/2005 (H5N1), which is more antigenically related to the challenge virus strain, in chickens.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21476487/