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Peer-reviewed veterinary case report

A new rat model of reversible global cerebral ischemia.

Journal:
Bulletin of experimental biology and medicine
Year:
2012
Authors:
Shcherbak, N S et al.
Affiliation:
V. A. Almazov Federal Center of the Heart
Species:
rodent

Abstract

A new rat model of global cerebral ischemia-reperfusion was proposed via reversible occlusion of the major vessels originating from the aortic arch and supplying the brain. This technique can be used for the search and study of exogenous (pharmacological) and endogenous methods of brain protection from ischemia-reperfusion injury.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/22803158/