Peer-reviewed veterinary case report
A new genotype of border disease virus with implications for molecular diagnostics.
- Journal:
- Archives of virology
- Year:
- 2016
- Authors:
- Peletto, Simone et al.
- Affiliation:
- Istituto Zooprofilattico Sperimentale del Piemonte · Italy
Abstract
Border disease virus (BDV) is a (+) single-stranded RNA pestivirus affecting mainly sheep and goats worldwide. Genetic typing of BDV has led to the identification of at least seven major genotypes. This study reports the detection of a BDV strain from a goat in northwestern Italy during routine investigations. Sequence analysis revealed mutations in the 5'-UTR of the virus with implications for BDV molecular diagnostics. Moreover, subsequent phylogenetic analysis based on the combined 5'-UTR and Npro/partial C genes, showed divergence from known BDV genotypes, revealing the detection of a novel pestivirus group, for which we propose the name BDV genotype 8.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/26597186/