Peer-reviewed veterinary case report
A new Down syndrome rat model races forward.
- Journal:
- Trends in genetics : TIG
- Year:
- 2022
- Authors:
- Roper, Randall J & Goodlett, Charles R
- Affiliation:
- Department of Biology · United States
- Species:
- rodent
Abstract
Animal models of Down syndrome (DS) provide an essential resource for understanding genetic, cellular, and molecular contributions to traits associated with trisomy 21 (Ts21). Recent genetic enhancements in the development of DS models, including the new TcHSA21rat model (Kazuki et al.), have potential to transform our understanding of and potential therapies for Ts21.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/35581033/