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Peer-reviewed veterinary case report

A multimodal approach to Canine Osteoarthritis management: A state-of-the-art.

Journal:
Open veterinary journal
Year:
2025
Authors:
Bougherara, Hithem et al.
Affiliation:
Gestion de la Sant&#xe9
Species:
dog

Plain-English summary

Canine osteoarthritis (OA) is a common and painful joint condition in dogs that gets worse over time and affects their quality of life. Since there is no cure for OA, the focus has shifted to a combination of treatments that can help manage the symptoms and improve the dog's well-being. These treatments may include managing the dog's weight, physical therapy, medications like anti-inflammatory drugs, and other therapies that help protect the joints. The review suggests that creating a personalized treatment plan for each dog is important for achieving the best results. Overall, the approach aims to help dogs with OA feel better and maintain a good quality of life.

Abstract

Canine osteoarthritis (OA) is a prevalent, progressive, and debilitating joint disorder characterized by cartilage degradation, synovial inflammation, and subchondral bone remodeling. This multifactorial disease leads to chronic pain and significant impairment of quality of life. As OA remains incurable, therapeutic strategies have shifted toward comprehensive multimodal management aimed at addressing the disease's complex pathophysiology. This review presents an evidence-based overview of current approaches, including weight management, rehabilitation, pharmacologic therapies (Non-Steroidal Anti-Inflammatory Drugs, anti-Nerve Growth Factor monoclonal antibodies), disease-modifying osteoarthritis drugs, regenerative treatments, and nutraceuticals. This study also highlights practical challenges and future directions, emphasizing individualized treatment plans to optimize outcomes in canine OA.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/41630707/