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Peer-reviewed veterinary case report

A long term feed supplementation based on phosphate binders in Feline Chronic Kidney Disease.

Journal:
Veterinary research communications
Year:
2018
Authors:
Biasibetti, E et al.
Affiliation:
University of Turin · Italy
Species:
cat

Plain-English summary

Chronic kidney disease (CKD) is a common issue in older cats, and a special diet can help improve their quality of life and longevity. In this study, researchers looked at 20 cats with advanced CKD, dividing them into two groups: one group received a dietary supplement for a year, while the other group only followed a renal diet. The supplement included ingredients like calcium and chitosan, and the owners provided feedback on their cats' appetite, health, and any vomiting or diarrhea. The results showed that the supplement helped lower phosphorus levels and increase bicarbonate levels in the cats without causing any negative side effects. Overall, the treatment was effective, and all the cats completed the study successfully.

Abstract

Chronic kidney disease (CKD) is a very common disorder in elderly cats. A proper renal diet represents the most efficient therapeutic intervention to improve survival and life quality in feline patients with 3 and 4 International Renal Interest Society (IRIS) stages. Twenty cats were selected in this study. Ten were administered the dietary supplementation for 360 days and the other ten, whose owners did not give consent for any supplemental therapies apart from the renal diet, were selected from a clinical database and used as control group. The present study is a long term study (360 days) aiming to evaluate the efficacy and palatability of a dietary supplementation containing calcium carbonate, calcium-lactate gluconate, chitosan and sodium bicarbonate in cats diagnosed with 3 and 4 IRIS stages of CKD. The owners were asked to fill in questionnaires to get information on the cat's appetite, the palatability of the given supplement, the presence of vomit and/or diarrhoea, general health and vitality. Hematochemical, biochemical and urinary analyses were performed on day 0, 30, 60, 90, 120, 150,180 and 360. GraphPad Prism® software was used to perform statistical analysis. Our study shows that the given dietary supplement reduced serum phosphorus and increased serum bicarbonate values in cats with CKD. In turn, this supplement could be used as a support therapy in cats with advanced CKD improving their clinical conditions without any adverse reaction. Finally, it is important to underline that all the animals completed the study and the owners reported a good palatability of the feed supplement.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/29582226/