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Peer-reviewed veterinary case report

A dog with acute myelomonocytic leukemia.

Journal:
The Journal of veterinary medical science
Year:
2008
Authors:
Hisasue, Masaharu et al.
Affiliation:
Azabu University · Japan
Species:
dog

Abstract

A three-year-old dog with marked leukocytosis, lymphadenopathy, and diarrhea showed an increase in unidentified blasts in the peripheral blood, and they were proliferated in the bone marrow. The dog was diagnosed with myelomonocytic leukemia (M4) because the blast cells were demonstrated by cytochemical staining to be both myeloid and monocytic cells. Although the dog was treated with a multi-combination chemotherapy and induction therapy using vitamin K2, it died on day 47 after the first admission. This case is the first report of M4 in Japan.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/18628605/