Peer-reviewed veterinary case report
A case of interstitial pneumonia associated with Pneumocystis carinii in a foal.
- Journal:
- Veterinary pathology
- Year:
- 1999
- Authors:
- Perron Lepage, M F et al.
- Affiliation:
- Dé · France
- Species:
- horse
Plain-English summary
A 3-month-old Swiss warmblood foal developed a serious lung infection called interstitial pneumonia, which is when the tissue in the lungs becomes inflamed and damaged. The foal suddenly had trouble breathing, and unfortunately, the condition was fatal. Tests showed that the foal's immune system was functioning normally, as there were no signs of immunosuppression, which means it wasn't lacking the ability to fight infections. The study also discusses how certain infections can affect the lungs of young foals. Sadly, the treatment did not work, and the foal did not survive.
Abstract
Subacute interstitial pneumonia with diffuse alveolar damage, marked macrophage infiltration, and intracellular Pneumocystis carinii cysts is described in a 3-month-old Swiss warmblood foal. Clinically, the disease was characterized by sudden onset of respiratory distress with fatal outcome. Based on serum immunoglobulin G (IgG), IgA, and IgM values, no humoral immunosuppression was detected. Spleen, thymus, and bronchial lymph nodes did not reveal lymphoid depletion, as assessed by immunohistochemical staining of CD-3-positive cells. Immunopathogenesis of pulmonary infections with intracellular agents in foals is discussed.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/10568448/