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Peer-reviewed veterinary case report

A canine case of necrotizing meningoencephalitis for long-term observation: clinical and MRI findings.

Journal:
The Journal of veterinary medical science
Year:
2007
Authors:
Kitagawa, Masato et al.
Affiliation:
Department of Veterinary Medicine · Japan
Species:
dog

Plain-English summary

A 3-year-old female pug had a seizure that started as a partial seizure and then progressed to more severe seizures over the next four years until she passed away. During this time, she showed signs of confusion, muscle jerks, and various types of seizures, eventually becoming unable to stand and showing signs of dementia. An MRI scan showed that her brain was shrinking as the disease progressed. After examining her brain tissue, the diagnosis was necrotizing meningoencephalitis, which is a serious brain condition. Unfortunately, despite the long observation period, the outcome was not favorable, and the dog eventually died from the disease.

Abstract

A 3-year-old female pug presented with general seizure following a partial seizure. During the remaining 48 months till death, the dog showed various neurological signs such as disturbance of consciousness, myoclonus and various types of partial seizure after each occurrence of the seizure clusters, and the dog eventually exhibited inability to stand and dementia. Magnetic resonance imaging findings revealed atrophy of the brain over the course of the disease. On histopathological analysis, the dog was diagnosed with necrotizing meningoencephalitis. This case of a canine necrotizing meningoencephalitis observed over the long term is valuable.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/18057839/